Mouse ADAM Metallopeptidase With Thrombospondin Type 1 Motif 20 (ADAMTS20) ELISA Kit

Product specifications

ELISA Kits

ADAM Metallopeptidase With Thrombospondin Type 1 Motif 20 (ADAMTS20)

Mouse

Colorimetric

Quantitative

Sandwich

0.156 ng/ml - 10 ng/ml

Optimal dilutions/concentrations should be determined by the end user.

96 tests

Lyophilized

ELISA

Serum, plasma and other biological fluids.

Shipped within 5-12 working days. The validity for this kit is 6 months.

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

No

P59511

GON-1,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 20,ADAMTS-20,ADAM-TS20

Elisa kits for ADAMTS20

RUO

Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ADAMTS20, also known as A Disintegrin And Metalloproteinase with Thrombospondin Motifs 20, is a member of the ADAMTS protein family .ADAMTS20, like other members of the ADAMTS family, contains multiple domains including a metalloproteinase domain responsible for its enzymatic activity, as well as thrombospondin type-1 (TSP-1) motifs. The precise function of ADAMTS20 is not fully understood, but it is believed to be involved in various biological processes, including extracellular matrix remodeling, tissue development, and possibly cell migration and adhesion. Studies have suggested potential roles for ADAMTS20 in skeletal development, as well as in the formation and maintenance of other tissues.Mutations in the ADAMTS20 gene have been associated with several genetic disorders, including Weill-Marchesani syndrome (WMS) and recessive isolated ectopia lentis (RIEL). WMS is characterized by short stature, brachydactyly (short fingers), joint stiffness, and eye abnormalities such as microspherophakia (small, spherical lenses) and ectopia lentis (dislocated lenses). RIEL is a milder form of ectopia lentis, characterized by dislocated lenses without other systemic features.

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