Human ADAMTS20 (A disintegrin and metalloproteinase with thrombospondin motifs 20) ELISA Kit
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Name
Human ADAMTS20 (A disintegrin and metalloproteinase with thrombospondin motifs 20) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH1793
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 78.125-5000pg/ml |
| Sensitivity | 46.875pg/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P59510 |
| Alias | GON-1,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 20,ADAMTS-20,ADAM-TS20 |
| Background | Elisa kits for ADAMTS20 |
| Status | RUO |
Background
ADAMTS20, also known as A Disintegrin And Metalloproteinase with Thrombospondin Motifs 20, is a member of the ADAMTS protein family .ADAMTS20, like other members of the ADAMTS family, contains multiple domains including a metalloproteinase domain responsible for its enzymatic activity, as well as thrombospondin type-1 (TSP-1) motifs. The precise function of ADAMTS20 is not fully understood, but it is believed to be involved in various biological processes, including extracellular matrix remodeling, tissue development, and possibly cell migration and adhesion. Studies have suggested potential roles for ADAMTS20 in skeletal development, as well as in the formation and maintenance of other tissues.Mutations in the ADAMTS20 gene have been associated with several genetic disorders, including Weill-Marchesani syndrome (WMS) and recessive isolated ectopia lentis (RIEL). WMS is characterized by short stature, brachydactyly (short fingers), joint stiffness, and eye abnormalities such as microspherophakia (small, spherical lenses) and ectopia lentis (dislocated lenses). RIEL is a milder form of ectopia lentis, characterized by dislocated lenses without other systemic features.
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