Mouse Acyl-coenzyme A thioesterase 8 (ACOT8) ELISA Kit

Este producto es parte de ACOT - Acyl-CoA Thioesterase
Mouse Acyl-coenzyme A thioesterase 8 (ACOT8) ELISA Kit
715€ (96 tests)

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Name
Mouse Acyl-coenzyme A thioesterase 8 (ACOT8) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx500833
Tested Applications
ELISA

Description

Mouse Acyl-coenzyme A thioesterase 8 (ACOT8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Acyl-coenzyme A thioesterase 8 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Acyl-coenzyme A thioesterase 8 (ACOT8)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P58137
Gene ID
170789
Alias
hTE,NAP1,PTE1,PTE2,PTE-1,PTE-2,HNAACTE,hACTE-III
Background
Elisa Kits for: ACOT8
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

ACOT8 is a ubiquitously expressed peroxisomal enzyme that hydrolyzes a wide range of acyl-CoA substrates, from short- to long-chain fatty acids, contributing to diverse metabolic processes. It plays a vital role in peroxisomal β-oxidation, bile acid synthesis, and the detoxification of reactive lipid intermediates. ACOT8 is particularly active in tissues such as the liver, kidney, and adrenal glands, where it regulates lipid and energy metabolism under conditions of metabolic stress or dietary changes. It also modulates the availability of CoA, ensuring the proper functioning of CoA-dependent enzymes within peroxisomes. Dysregulation of ACOT8 activity has been implicated in metabolic syndromes, including obesity and non-alcoholic fatty liver disease, where altered lipid metabolism affects systemic energy balance. Its broad substrate specificity and enzymatic versatility make ACOT8 a critical player in maintaining peroxisomal and cellular metabolic homeostasis.

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