Mouse Acyl-coenzyme A thioesterase 11 (ACOT11) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits ACOT11
proveedor
Abbexareference
abx500802Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Acyl-coenzyme A thioesterase 11 (ACOT11) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Acyl-coenzyme A thioesterase 11 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ACOT11, also known as BFIT (Brown Fat-Inducible Thioesterase), is a cytosolic enzyme involved in the hydrolysis of medium- and long-chain acyl-CoA esters, with a specific role in thermogenesis and energy expenditure. It is highly expressed in brown adipose tissue, where it regulates fatty acid mobilization and provides substrates for heat production through mitochondrial uncoupling. ACOT11 plays a crucial role in lipid metabolism during periods of cold exposure or metabolic stress, ensuring an adequate supply of free fatty acids for β-oxidation and thermogenic activity. In addition to its role in brown fat, ACOT11 is expressed in other tissues, where it contributes to lipid signaling and metabolic homeostasis. Dysregulation of ACOT11 has been implicated in metabolic syndromes such as obesity and insulin resistance, making it a potential target for therapies aimed at enhancing energy expenditure and combating metabolic diseases.
Características del producto
category
ELISA Kits
immunogen target
Acyl-coenzyme A thioesterase 11 (ACOT11)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
BFIT,THEA,THEM1,STARD14
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
ACOT11
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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