Mouse Acyl-CoA Dehydrogenase Family Member 8 (ACAD8) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Acyl-CoA Dehydrogenase Family Member 8 (ACAD8) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500584
tested applications
ELISA
Description
Mouse Acyl-CoA Dehydrogenase Family Member 8 (ACAD8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Acyl-CoA Dehydrogenase Family Member 8 (ACAD8) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Acyl-CoA Dehydrogenase Family Member 8 (ACAD8) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9D7B6 |
| Gene ID | 66948 |
| Alias | ACAD-8,ARC42,IBDH |
| Background | Elisa kits for ACAD8 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACAD8 is a mitochondrial enzyme involved in the catabolism of isoleucine, a branched-chain amino acid, through its role in the propionyl-CoA pathway. It catalyzes the dehydrogenation of isobutyryl-CoA, an essential step in the breakdown of isoleucine into intermediates that can enter the tricarboxylic acid (TCA) cycle for energy production. ACAD8 is expressed predominantly in tissues with high metabolic activity, including the liver and muscles, where branched-chain amino acid metabolism is critical for energy balance. Mutations in the ACAD8 gene are associated with isobutyryl-CoA dehydrogenase deficiency, a rare metabolic disorder characterized by elevated levels of isobutyryl-carnitine and potential metabolic acidosis. Its role in amino acid metabolism underscores its importance in both energy production and metabolic regulation, particularly during periods of increased energy demand, such as fasting or physical exertion.
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