Mouse Acyl-CoA Dehydrogenase Family Member 8 (ACAD8) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ACAD8
proveedor
Abbexareference
abx500584Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Acyl-CoA Dehydrogenase Family Member 8 (ACAD8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Acyl-CoA Dehydrogenase Family Member 8 (ACAD8) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ACAD8 is a mitochondrial enzyme involved in the catabolism of isoleucine, a branched-chain amino acid, through its role in the propionyl-CoA pathway. It catalyzes the dehydrogenation of isobutyryl-CoA, an essential step in the breakdown of isoleucine into intermediates that can enter the tricarboxylic acid (TCA) cycle for energy production. ACAD8 is expressed predominantly in tissues with high metabolic activity, including the liver and muscles, where branched-chain amino acid metabolism is critical for energy balance. Mutations in the ACAD8 gene are associated with isobutyryl-CoA dehydrogenase deficiency, a rare metabolic disorder characterized by elevated levels of isobutyryl-carnitine and potential metabolic acidosis. Its role in amino acid metabolism underscores its importance in both energy production and metabolic regulation, particularly during periods of increased energy demand, such as fasting or physical exertion.
Características del producto
category
ELISA Kits
immunogen target
Acyl-CoA Dehydrogenase Family Member 8 (ACAD8)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
ACAD-8,ARC42,IBDH
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ACAD8
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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