Acyl-CoA Dehydrogenase Family Member 8 (ACAD8) Antibody

Este producto es parte de ACAD - Acyl-CoA Dehydrogenase
Acyl-CoA Dehydrogenase Family Member 8 (ACAD8) Antibody

Pida mas información

935106861

info@markelab.com

Precio

250€ (80 µl)

Antibody anti-ACAD8

proveedor

Abbexa

reference

abx034392

Tested Applications

ELISA, WB

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

Descripción

ACAD8 is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. This protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine.


Background

ACAD8 is a mitochondrial enzyme involved in the catabolism of isoleucine, a branched-chain amino acid, through its role in the propionyl-CoA pathway. It catalyzes the dehydrogenation of isobutyryl-CoA, an essential step in the breakdown of isoleucine into intermediates that can enter the tricarboxylic acid (TCA) cycle for energy production. ACAD8 is expressed predominantly in tissues with high metabolic activity, including the liver and muscles, where branched-chain amino acid metabolism is critical for energy balance. Mutations in the ACAD8 gene are associated with isobutyryl-CoA dehydrogenase deficiency, a rare metabolic disorder characterized by elevated levels of isobutyryl-carnitine and potential metabolic acidosis. Its role in amino acid metabolism underscores its importance in both energy production and metabolic regulation, particularly during periods of increased energy demand, such as fasting or physical exertion.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human, Mouse


immunogen target

Acyl-CoA Dehydrogenase Family Member 8 (ACAD8)


host

Rabbit


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB


purification

Purified through a protein A column, followed by peptide affinity purification.


buffer

PBS containing 0.09% sodium azide.


size 1

80 µl


size 2

400 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

ACAD8


dry ice

No


availability

Shipped within 5-10 working days.


alias

ACAD-8,ARC42,IBDH


note

This product is for research use only.


Quizá le pueda interesar

anti- ACAD8 antibody

anti- ACAD8 antibody

proveedor

FineTest

reference

FNab00061

Tested Applications

ELISA, WB

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Has very high activity toward isobutyryl-CoA. Is an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Pl...

Precio a consultar

Ver más

Recombinant Human ACAD8

Recombinant Human ACAD8

proveedor

FineTest

reference

P6962

Tested Applications

Western Blot,ELISA

status

RUO

Precio a consultar

Ver más

Acyl-CoA Dehydrogenase Family Member 8 (ACAD8) Antibody

Acyl-CoA Dehydrogenase Family Member 8 (ACAD8) Antibody

proveedor

Abbexa

reference

abx034392

Tested Applications

ELISA, WB

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

ACAD8 is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivati...

250€ (80 µl)

Ver más