Mouse Acrosin (ACR) ELISA Kit
715€ (96 tests)
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935106861
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name
Mouse Acrosin (ACR) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx518912
tested applications
ELISA
Description
Mouse Acrosin (ACR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Acrosin (ACR) concentrations in serum, plasma and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Acrosin (ACR) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P23578 |
| Alias | SPGF87 |
| Background | Elisa kits for ACR |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Acrosin (ACR) is a serine protease enzyme localized in the acrosome of spermatozoa, where it plays a critical role in the fertilization process. It is synthesized as an inactive zymogen called proacrosin, which is activated during the acrosome reaction to assist in the penetration of the sperm through the zona pellucida, the outer glycoprotein layer of the oocyte. Acrosin functions by hydrolyzing zona pellucida proteins and facilitating sperm binding to the egg, making it essential for successful fertilization. The activity of acrosin is tightly regulated to prevent premature activation, ensuring that it is only active during the fertilization process. Dysregulation or mutations affecting acrosin function have been associated with male infertility due to impaired sperm-oocyte interaction. Acrosin is also studied as a marker for sperm acrosomal integrity and functionality in reproductive biology and clinical diagnostics. Research into acrosin inhibitors is being explored as a potential strategy for developing non-hormonal contraceptives.
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