Mouse Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) ELISA Kit

Este producto es parte de ACSS - Acyl-CoA Synthetase Short-Chain Family Member
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500867
tested applications
ELISA

Description

Mouse Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Acetyl-coenzyme A synthetase, cytoplasmic concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.07 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9QXG4
Gene ID
60525
Alias
ACAS2,ACECS,ACS,ACSA
Background
Elisa kits for ACSS2
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ACSS2 is a cytosolic and nuclear enzyme that catalyzes the activation of acetate into acetyl-CoA, playing a central role in lipid synthesis, histone acetylation, and energy metabolism. It is highly expressed in the liver, adipose tissue, and brain, where it contributes to diverse metabolic and regulatory processes. In the nucleus, ACSS2 provides acetyl-CoA for histone acetylation, influencing gene expression and cellular responses to environmental changes. In the cytoplasm, it supports lipogenesis and cholesterol synthesis by activating acetate for incorporation into fatty acids and sterols. ACSS2 also plays a role in cancer metabolism by providing acetyl-CoA to fuel biosynthetic pathways in rapidly proliferating cells. Dysregulation of ACSS2 has been implicated in cancer progression, metabolic syndromes, and neurodegenerative diseases, highlighting its critical function in integrating metabolic and epigenetic regulation.

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