Mouse A-Kinase Anchor Protein 8 Like (AKAP8L) ELISA Kit
715€ (96 tests)
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Name
Mouse A-Kinase Anchor Protein 8 Like (AKAP8L) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx388479
Tested Applications
ELISA
Description
Mouse A-Kinase Anchor Protein 8 Like (AKAP8L) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse A-Kinase Anchor Protein 8 Like (AKAP8L) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | A-Kinase Anchor Protein 8 Like (AKAP8L) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | < 46.9 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9R0L7 |
| Alias | NAKAP, NAKAP95 |
| Background | Elisa Kits for: AKAP8L |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
A Kinase Anchor Protein 8-Like (AKAP8L) is a member of the AKAP family of scaffolding proteins that anchor protein kinase A (PKA) and other signaling molecules to specific subcellular locations, thereby compartmentalizing signaling pathways. AKAP8L is predominantly localized in the nucleus, where it plays a critical role in RNA processing, chromatin remodeling, and transcriptional regulation. It is involved in coordinating events such as mRNA splicing and nuclear export, and it may also contribute to mitotic progression through its interactions with chromatin-associated proteins. AKAP8L facilitates the integration of signaling cascades with gene expression, highlighting its role in cellular adaptation to external and internal cues. Dysregulation of AKAP8L has been implicated in cancer and other diseases, where disrupted nuclear signaling and chromatin dynamics affect cell proliferation and survival. Emerging research suggests AKAP8L’s involvement in stress responses, particularly in modulating nuclear processes under conditions of DNA damage or oxidative stress, making it a potential target for therapeutic intervention.
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