Mouse A Disintegrin And Metalloprotease 15 (ADAM15) Protein (Active)
1235€ (100 µg)
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935106861
info@markelab.com
name
Mouse A Disintegrin And Metalloprotease 15 (ADAM15) Protein (Active)
category
Proteins and Peptides
provider
Abbexa
reference
abx692224
tested applications
SDS-PAGE
Description
Mouse ADAM15 Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse ADAM15 (O88839-1) extracellular domain (Met 1-Thr 697) was expressed, with a C-terminal polyhistidine tag.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | ADAM15 |
| Host | HEK293 cells |
| Origin | Mouse |
| Observed MW | Molecular Weight: 74.6 kDa Sequence Fragment: Met1-Thr697 Tag: C-terminal His tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O88839-1 |
| Alias | MDC15,MDC-15,Metargidin,ADAM-15 |
| Background | Protein ADAM15 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ADAM15, also known as ADAM metallopeptidase domain 15, is a member of the ADAM (a disintegrin and metalloproteinase) family . These proteins are involved in various biological processes, including cell adhesion, migration, proteolysis, and signaling. ADAM15 is a transmembrane protein, meaning it spans the cell membrane, with both extracellular and intracellular domains.ADAM15 consists of several distinct domains, including a metalloproteinase domain responsible for its proteolytic activity, a disintegrin domain involved in cell-cell and cell-matrix interactions, a cysteine-rich domain, an EGF-like domain, a transmembrane domain, and a cytoplasmic tail.ADAM15 is implicated in various physiological and pathological processes, including cell adhesion, migration, proliferation, and signaling. It can cleave cell surface proteins, releasing soluble forms of these proteins into the extracellular environment. Is also involved in cell-cell and cell-matrix interactions. It interacts with various proteins on the cell surface and in the extracellular matrix, including integrins, growth factors, cytokines, and cell adhesion molecules.ADAM15 has been linked to cancer progression and metastasis. Its expression is often elevated in various cancers, including breast, lung, colon, prostate, and pancreatic cancers. ADAM15 can promote tumor cell invasion and metastasis by facilitating cell migration and invasion through the extracellular matrix.
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