A Disintegrin And Metalloprotease 15 (ADAM15) Antibody
312€ (60 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
A Disintegrin And Metalloprotease 15 (ADAM15) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx007052
tested applications
WB, IF/ICC
Description
ADAM15 Antibody is a Rabbit Polyclonal Antibody against ADAM15.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | A Disintegrin And Metalloprotease 15 (ADAM15) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13444 |
| Gene ID | 8751 |
| NCBI Accession | NP_003806.3 |
| Alias | MDC15,MDC-15,Metargidin,ADAM-15 |
| Background | Antibody anti-ADAM15 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
ADAM15, also known as ADAM metallopeptidase domain 15, is a member of the ADAM (a disintegrin and metalloproteinase) family . These proteins are involved in various biological processes, including cell adhesion, migration, proteolysis, and signaling. ADAM15 is a transmembrane protein, meaning it spans the cell membrane, with both extracellular and intracellular domains.ADAM15 consists of several distinct domains, including a metalloproteinase domain responsible for its proteolytic activity, a disintegrin domain involved in cell-cell and cell-matrix interactions, a cysteine-rich domain, an EGF-like domain, a transmembrane domain, and a cytoplasmic tail.ADAM15 is implicated in various physiological and pathological processes, including cell adhesion, migration, proliferation, and signaling. It can cleave cell surface proteins, releasing soluble forms of these proteins into the extracellular environment. Is also involved in cell-cell and cell-matrix interactions. It interacts with various proteins on the cell surface and in the extracellular matrix, including integrins, growth factors, cytokines, and cell adhesion molecules.ADAM15 has been linked to cancer progression and metastasis. Its expression is often elevated in various cancers, including breast, lung, colon, prostate, and pancreatic cancers. ADAM15 can promote tumor cell invasion and metastasis by facilitating cell migration and invasion through the extracellular matrix.
Related Products
A Disintegrin And Metalloprotease 15 (ADAM15) Antibody
ADAM15 Antibody is a Rabbit Polyclonal Antibody against ADAM15.
Ver Producto
A Disintegrin And Metalloprotease 15 (ADAM15) Antibody
Rabbit Polyclonal against the ADAM15 protein.
Ver ProductoA Disintegrin And Metalloprotease 15 (ADAM15) Antibody
Rabbit Polyclonal against the ADAM15 protein.
Ver Producto