Mouse 5-hydroxytryptamine receptor 1F (HTR1F) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse 5-hydroxytryptamine receptor 1F (HTR1F) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500187
tested applications
ELISA
Description
Mouse 5-hydroxytryptamine receptor 1F (HTR1F) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse 5-hydroxytryptamine receptor 1F concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | 5-hydroxytryptamine receptor 1F (HTR1F) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q02284 |
| Gene ID | 15557 |
| Alias | HTR1F,5HT6, MR77, 5-HT1F, HTR1EL, 5-HT-1F,5-HT1F receptor |
| Background | Elisa kits for HTR1F |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
HTR1F is a G protein-coupled receptor (GPCR) and a member of the serotonin receptor family, involved in mediating serotonin's effects on neuronal signaling, vasoconstriction, and pain modulation. HTR1F is predominantly expressed in the trigeminal nerve pathways and meningeal blood vessels, where it regulates vascular tone and inflammatory responses. It is most well-known for its role in the treatment of migraine headaches, where activation of HTR1F receptors leads to the inhibition of pain transmission without causing vasoconstriction, unlike other serotonin receptors. Selective agonists, such as lasmiditan, specifically target HTR1F to relieve migraine symptoms by reducing the excitability of trigeminal neurons and limiting the release of pro-inflammatory neuropeptides. In addition to its role in migraine management, HTR1F may contribute to modulating mood, anxiety, and cognitive functions. Its unique ability to alleviate migraine pain without affecting vascular constriction makes it a safer alternative for individuals with cardiovascular risks. Ongoing research into HTR1F's mechanisms of action highlights its potential as a therapeutic target not only for migraine treatment but also for neuroinflammatory conditions, mood stabilization, and pain-related disorders.
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