Mouse 3-ketoacyl-CoA thiolase A, peroxisomal (ACAA1A) ELISA Kit

Name: Mouse 3-ketoacyl-CoA thiolase A, peroxisomal (ACAA1A) ELISA Kit
Brand: Abbexa
SKU: abx549577
Price: 715 EUR
Availability: OnlineOnly

Este producto es parte de ACAA - Acetyl Coenzyme A Acyltransferase

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ACAA1A

proveedor

Abbexa

reference

abx549577

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse 3-ketoacyl-CoA thiolase A, peroxisomal (ACAA1A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse 3-ketoacyl-CoA thiolase A, peroxisomal concentrations in tissue homogenates, cell lysates and other biological fluids.

Background

Acetyl Coenzyme A Acyltransferase 1A (ACAA1A) is a peroxisomal enzyme that plays a critical role in the beta-oxidation pathway, facilitating the breakdown of long-chain and branched-chain fatty acids into acetyl-CoA and shorter acyl-CoA molecules. ACAA1A functions as a thiolase, catalyzing the final step in fatty acid degradation, which is essential for lipid homeostasis and energy production, particularly during fasting or other conditions where fatty acids serve as the primary energy source. ACAA1A is highly expressed in tissues with active lipid metabolism, including the liver, kidneys, and adipose tissue. Mutations or deficiencies in ACAA1A activity can lead to peroxisomal disorders, such as Zellweger syndrome or adrenoleukodystrophy, characterized by the accumulation of very-long-chain fatty acids and associated metabolic dysfunctions. ACAA1A is also of interest in studies on metabolic reprogramming in cancer, as its role in fatty acid oxidation may influence tumor growth and progression.

Características del producto

immunogen target

3-ketoacyl-CoA thiolase A, peroxisomal (ACAA1A)

reactivity

Mouse

test range

0.156 ng/ml - 10 ng/ml

assay data

Quantitative

form

Lyophilized

detection method

Colorimetric

sample type

Tissue homogenates, cell lysates and other biological fluids.

size 1

96 tests

alias

Acaa, Acaa1

storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

or code

ACAA1A

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q921H8

gene id

https://www.ncbi.nlm.nih.gov/gene/113868

note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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