Mouse 1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (AGPAT2) ELISA Kit
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Description
Mouse 1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (AGPAT2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse AGPAT2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | 1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (AGPAT2) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | < 46.9 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8K3K7 |
| Gene ID | 67512 |
| Alias | 1-AGPAT2,BSCL,BSCL1 |
| Background | Elisa kits for AGPAT2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AGPAT2 is a central enzyme in triglyceride and phospholipid biosynthesis, catalyzing the acylation of lysophosphatidic acid (LPA) to produce phosphatidic acid (PA). AGPAT2 is predominantly expressed in adipose tissue, where it regulates the production of glycerophospholipids and triglycerides. It plays a vital role in adipogenesis and lipid storage, contributing to the formation of functional lipid droplets. Mutations in the AGPAT2 gene are linked to congenital generalized lipodystrophy type 1 (CGL1), a disorder characterized by the near absence of adipose tissue, insulin resistance, and hypertriglyceridemia. The loss of AGPAT2 activity disrupts lipid metabolism, resulting in severe metabolic dysfunction.
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1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (AGPAT2) Antibody
AGPAT2 Antibody is a Rabbit Polyclonal antibody against AGPAT2. This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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