Mothers Against Decapentaplegic Homolog 4 (SMAD4) Antibody
383.5€ (100 µl)
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Name
Mothers Against Decapentaplegic Homolog 4 (SMAD4) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx015994
Tested Applications
ELISA, WB, IHC, IF/ICC, FCM
Description
Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily; SMAD4 is the common SMAD (co-SMAD).Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription.May act as a tumor suppressor. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Mothers Against Decapentaplegic Homolog 4 (SMAD4) Immunogen: Purified recombinant fragment of human SMAD4 expressed in E. coli. |
| Host | Mouse |
| Reactivity | Human, Mouse |
| Assay Type | Concentration: Not determined. |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Observed MW | 65 kDa |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13485 |
| Gene ID | 4089 |
| OMIM | 114500 |
| Background | Antibody anti-SMAD4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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