Mitotic Checkpoint Serine/threonine-Protein Kinase BUB1 (BUB1) Antibody
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Description
Rabbit polyclonal antibody against BUB1 protein. Immunogen region is Internal.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 (BUB1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/40000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43683 |
| Gene ID | 699 |
| OMIM | 602452 |
| Background | Antibody anti-BUB1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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BUB1 antibody
This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.
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Mitotic Checkpoint Serine/threonine-Protein Kinase BUB1 (BUB1) Antibody
BUB1 Antibody is a Rabbit Polyclonal antibody against BUB1. This gene encodes a Serine/Threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.
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Mitotic Checkpoint Serine/threonine-Protein Kinase BUB1 (BUB1) Antibody
Rabbit polyclonal antibody against BUB1 protein. Immunogen region is Internal.
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