Mitotic Checkpoint Serine/threonine-Protein Kinase BUB1 (BUB1) Antibody
195€ (20 µl)
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Name
Mitotic Checkpoint Serine/threonine-Protein Kinase BUB1 (BUB1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx001575
Tested Applications
ELISA, WB
Description
BUB1 Antibody is a Rabbit Polyclonal antibody against BUB1. This gene encodes a Serine/Threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Mitotic Checkpoint Serine/Threonine-Protein Kinase BUB1 (BUB1) Immunogen: Recombinant protein corresponding to BUB1. The exact sequence is proprietary. |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 122 kDa Observed MW: 133 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43683 |
| Gene ID | 699 |
| NCBI Accession | NP_004327.1 |
| OMIM | 602452 |
| Background | Antibody anti-BUB1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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