Microfibrillar Associated Protein 2 (MFAP2) Antibody
286€ (100 µl)
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935106861
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name
Microfibrillar Associated Protein 2 (MFAP2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx128849
tested applications
WB, IHC, IF/ICC
Description
Microfibrillar Associated Protein 2 Antibody is a Rabbit Polyclonal against Microfibrillar Associated Protein 2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Microfibrillar Associated Protein 2 (MFAP2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | MAGP,MAGP1,MAGP-1,MFAP-2 |
| Background | Antibody anti-MFAP2 |
| Status | RUO |
Descripción
Microfibril Associated Protein 2 (MFAP2), also known as MAGP-1, is a component of the extracellular matrix associated with microfibrils. MFAP2 interacts with fibrillin and elastin to contribute to the structural integrity and elastic properties of connective tissues. It plays a role in modulating signaling pathways such as TGF-β and BMP, which are crucial for tissue homeostasis, repair, and development. Dysregulation of MFAP2 has been implicated in connective tissue disorders, including Marfan syndrome and aortic aneurysms, due to its impact on microfibril assembly and extracellular matrix stability. MFAP2 also has emerging roles in angiogenesis and tumor progression, where it influences the extracellular microenvironment and cell signaling.
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