Microfibrillar Associated Protein 2 (MFAP2) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Microfibrillar Associated Protein 2 (MFAP2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx028706
tested applications
ELISA, WB
Description
Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Four transcript variants encoding two different isoforms have been found for this gene.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Microfibrillar Associated Protein 2 (MFAP2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P55001 |
| Alias | MAGP,MAGP1,MAGP-1,MFAP-2 |
| Background | Antibody anti-MFAP2 |
| Status | RUO |
Descripción
Microfibril Associated Protein 2 (MFAP2), also known as MAGP-1, is a component of the extracellular matrix associated with microfibrils. MFAP2 interacts with fibrillin and elastin to contribute to the structural integrity and elastic properties of connective tissues. It plays a role in modulating signaling pathways such as TGF-β and BMP, which are crucial for tissue homeostasis, repair, and development. Dysregulation of MFAP2 has been implicated in connective tissue disorders, including Marfan syndrome and aortic aneurysms, due to its impact on microfibril assembly and extracellular matrix stability. MFAP2 also has emerging roles in angiogenesis and tumor progression, where it influences the extracellular microenvironment and cell signaling.
Related Products
Microfibrillar Associated Protein 2 (MFAP2) Antibody
Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Four transcript variants encoding two different isoforms have been found for this gene.
Ver Producto
Microfibrillar Associated Protein 2 (MFAP2) Antibody
Rabbit Polyclonal against the MFAP2 protein.
Ver Producto
Microfibrillar Associated Protein 2 (MFAP2) Antibody
Microfibrillar Associated Protein 2 Antibody is a Rabbit Polyclonal against Microfibrillar Associated Protein 2.
Ver Producto