Microfibril-Associated Glycoprotein 3 (MFAP3) Antibody

Este producto es parte de MFAP - microfibril associated protein
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169€ (20 µg)

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935106861
info@markelab.com
name
Microfibril-Associated Glycoprotein 3 (MFAP3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx304479
tested applications
ELISA

Description

MFAP3 Antibody is a Rabbit Polyclonal against MFAP3.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Microfibril-Associated Glycoprotein 3 (MFAP3)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P55082
Gene ID
4238
NCBI Accession
NP_001128509.1, NM_001135037.1, NP_001229265.1, NM_001242336.1
OMIM
600491
Alias
Microfibril-associated glycoprotein 3
Background
Antibody anti-MFAP3
Status
RUO

Descripción

Microfibril-Associated Protein 3 (MFAP3) is a member of the microfibril-associated protein (MFAP) family, which are integral components of the extracellular matrix (ECM) and are involved in the assembly and stabilization of microfibrils. These microfibrils are primarily composed of fibrillin and provide critical structural support to connective tissues. MFAP3 interacts with fibrillin-1 and other ECM components to contribute to tissue integrity and elasticity.  MFAP3 is characterized by regions rich in cysteine residues, which allow for the formation of disulfide bonds, crucial for stabilizing microfibril structure. MFAP3 is expressed in various tissues, particularly those with significant elastic properties, such as the lung, skin, vasculature, and ligaments. MFAP3 is believed to play a role in microfibril organization and elastogenesis—the process by which elastic fibers are formed and maintained. These fibers are essential for the elasticity and resilience of tissues subjected to repetitive mechanical stress.

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