Methyl-Cpg-Binding Domain Protein 2 (MBD2) Antibody
260€ (50 µg)
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935106861
info@markelab.com
name
Methyl-Cpg-Binding Domain Protein 2 (MBD2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx457336
tested applications
ELISA, WB, IHC
Description
Methyl-Cpg-Binding Domain Protein 2 (MBD2) Antibody is a Rabbit polyclonal antibody for the detection of Human Methyl-Cpg-Binding Domain Protein 2 (MBD2).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Methyl-Cpg-Binding Domain Protein 2 (MBD2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UBB5 |
| Gene ID | 8932 |
| NCBI Accession | NP_003918.1 |
| Background | Antibody anti-MBD2 |
| Status | RUO |
Descripción
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MBD2 antibody
Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
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