Human MBD2 (Methyl-CpG-binding domain protein 2) QuickTest ELISA Kit

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935106861
info@markelab.com
name
Human MBD2 (Methyl-CpG-binding domain protein 2) QuickTest ELISA Kit
category
ELISA Kits
provider
FineTest
reference
QT-EH9990
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Reactivity | Human |
Assay Data | 120 minutes |
Assay Type | Sandwich ELISA, Double Antibody |
Test Range | 15.625-1000pg/ml |
Sensitivity | 9.375pg/ml |
Size 1 | 96T |
Tested Applications | ELISA |
Sample Type | Serum, plasma, cell culture supernatant, cell lysate or tissue lysate, other biological fluid samples |
Availability | Shipped within 10-14 working days. |
Storage | 2-8 °C for 12 months |
Alias | Methyl-CpG-binding domain protein 2, MBD2, Demethylase, DMTase, Methyl-CpG-binding protein MBD2 |
Background | Elisa kits for MBD2 |
Status | RUO |
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Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
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