Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
MDC1 Antibody is a Rabbit Polyclonal Antibody against MDC1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Mediator Of DNA Damage Checkpoint 1 (MDC1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC-P: 1/100 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IHC, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q14676 |
| Gene ID | 9656 |
| NCBI Accession | NP_055456.2 |
| Background | Antibody anti-MDC1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Related Products

MDC1 antibody
The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
Ver Producto
Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody
MDC1 Antibody is a Rabbit Polyclonal Antibody against MDC1.
Ver Producto
Mediator Of DNA Damage Checkpoint 1 Phospho-Ser513 (MDC1 pS513) Antibody
Rabbit polyclonal antibody against MDC1 protein. Immunogen region is Internal. Specificity is as follows for the reactive species: H:S513.
Ver Producto