MAS1 Oncogene (MAS1) Antibody
221€ (50 µg)
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Name
MAS1 Oncogene (MAS1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx326994
Tested Applications
WB, IHC
Description
MAS1 Antibody is a Rabbit Polyclonal against MAS1.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: MAS1 Oncogene (MAS1) Immunogen: Synthetic Peptide. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/2000 - 1/5000, IHC: 1/200 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | WB, IHC |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P04201 |
| Gene ID | 4142 |
| Alias | MAS1,MAS,angiotensin 1-7 receptor ,MAS1 proto-oncogene G protein-coupled receptor,MAS1 proto-oncogene, MasR, Mgra |
| Background | Antibody anti-MAS1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
MAS1 is a gene that encodes a G protein-coupled receptor (GPCR) involved in various physiological processes, including cardiovascular regulation, neuronal signaling, and cellular proliferation. It was originally identified as a proto-oncogene due to its potential role in tumorigenesis. MAS1 is involved in signaling pathways that regulate the growth and differentiation of cells. It is also known for its interaction with the angiotensin peptide, particularly in the regulation of blood pressure and fluid balance. MAS1 functions in mediating the effects of angiotensin peptides on vascular smooth muscle and endothelial cells, contributing to vasodilation and regulating blood pressure. Studies suggest that MAS1 may play a protective role in cardiovascular health by modulating angiotensin-induced vasoconstriction. Dysregulation of MAS1 signaling has been implicated in various cancers and cardiovascular diseases, and research into its role as a tumor suppressor or oncogene could provide novel insights for therapeutic strategies.
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