MAS1 Oncogene (MAS1) Antibody
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Description
MAS1 Antibody is a Rabbit Polyclonal against MAS1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | MAS1 Oncogene (MAS1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/2000 - 1/5000, IHC: 1/200 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | WB, IHC |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P04201 |
| Gene ID | 4142 |
| Alias | MAS1,MAS,angiotensin 1-7 receptor ,MAS1 proto-oncogene G protein-coupled receptor,MAS1 proto-oncogene, MasR, Mgra |
| Background | Antibody anti-MAS1 |
| Status | RUO |
Descripción
MAS1 is a gene that encodes a G protein-coupled receptor (GPCR) involved in various physiological processes, including cardiovascular regulation, neuronal signaling, and cellular proliferation. It was originally identified as a proto-oncogene due to its potential role in tumorigenesis. MAS1 is involved in signaling pathways that regulate the growth and differentiation of cells. It is also known for its interaction with the angiotensin peptide, particularly in the regulation of blood pressure and fluid balance. MAS1 functions in mediating the effects of angiotensin peptides on vascular smooth muscle and endothelial cells, contributing to vasodilation and regulating blood pressure. Studies suggest that MAS1 may play a protective role in cardiovascular health by modulating angiotensin-induced vasoconstriction. Dysregulation of MAS1 signaling has been implicated in various cancers and cardiovascular diseases, and research into its role as a tumor suppressor or oncogene could provide novel insights for therapeutic strategies.
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