Lysophosphatidic acid receptor 6 (LPAR6) Antibody (FITC)
260€ (50 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Lysophosphatidic acid receptor 6 (LPAR6) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx344034
Description
Lysophosphatidic acid receptor 6 (LPAR6) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human LPAR6.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Lysophosphatidic acid receptor 6 (LPAR6) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Size 3 | 200 µl |
| Size 4 | 1 ml |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P43657 |
| Gene ID | 10161 |
| Alias | LPAR6,ARWH1,HYPT8,LAH3,LPA-6,P2RY5,P2Y5,LPA receptor 6,oleoyl-L-alpha-lysophosphatidic acid receptor,P2Y purinoceptor 5,purinergic receptor 5 |
| Background | Antibody anti-LPAR6 |
| Status | RUO |
Descripción
LPAR6, also known as P2Y5, is a G protein-coupled receptor activated by lysophosphatidic acid (LPA). It primarily couples to G12/13 proteins and plays a key role in cellular signaling related to cytoskeletal reorganization, cell migration, and proliferation. LPAR6 is predominantly expressed in hair follicles, skin, and epithelial tissues, where it regulates hair growth and skin homeostasis. Mutations in LPAR6 are associated with inherited hair disorders such as hypotrichosis and woolly hair syndrome, where impaired LPA signaling disrupts normal hair follicle function. Beyond its role in hair biology, LPAR6 contributes to epithelial cell survival and wound healing processes. LPAR6 has also been linked to cancer progression, particularly in promoting cell migration, metastasis, and resistance to apoptosis in epithelial cancers. Dysregulation of LPAR6 signaling has implications in skin disorders, inflammatory conditions, and tumor progression. LPAR6 represents a therapeutic target for managing hair growth disorders, epithelial repair, and cancer metastasis.
Related Products
LPAR6 Antibody
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene aligns with an internal intron of the retinoblastoma susceptibility gene in the reverse orientation. Alternative splicing results in multiple transcript variants.
Ver Producto
Lysophosphatidic acid receptor 6 (LPAR6) Antibody
Lysophosphatidic acid receptor 6 (LPAR6) Antibody is a Rabbit Polyclonal antibody for the detection of Human LPAR6.
Ver Producto