LRR Binding FLII Interacting Protein 2 (LRRFIP2) Antibody (HRP)
169€ (20 µg)
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935106861
info@markelab.com
name
LRR Binding FLII Interacting Protein 2 (LRRFIP2) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx336330
tested applications
ELISA
Description
LRRFIP2 Antibody (HRP) is a Rabbit Polyclonal against LRRFIP2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | LRR Binding FLII Interacting Protein 2 (LRRFIP2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y608 |
| Gene ID | 9209 |
| Alias | LRR FLII-interacting protein 2,HUFI-2 |
| Background | Antibody anti-LRRFIP2 |
| Status | RUO |
Descripción
Leucine-rich repeat flightless-interacting protein 2 (LRRFIP2) shares structural and functional similarities with LRRFIP1 and participates in several critical cellular processes. LRRFIP2 has been identified as a modulator of innate immune responses, particularly in the NOD-like receptor signaling pathway, where it regulates the activation of inflammasomes and production of IL-1β. It also interacts with flightless I and contributes to cytoskeletal organization, playing a role in cell shape and motility. LRRFIP2's involvement in transcriptional regulation is mediated by its ability to bind DNA and influence gene expression. Emerging evidence suggests that LRRFIP2 may play a role in metabolic pathways and autophagy, although these functions require further investigation. Altered expression or mutations in LRRFIP2 have been linked to inflammatory diseases and metabolic disorders, underscoring its importance in maintaining cellular and systemic homeostasis.
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