Low Sample Volume Mouse Interleukin 6 (IL6) ELISA Kit

Este producto es parte de IL6 - Interleukin 6
Low Sample Volume Mouse Interleukin 6 (IL6) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

637€ (96 tests)

Elisa kits for IL6

proveedor

Abbexa

reference

abx052083

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Interleukin 6 (IL6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Interleukin 6 (IL6) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Interleukin 6 (IL6)


Background

IL6 is a pleiotropic cytokine involved in regulating immune responses, inflammation, and hematopoiesis It is produced by macrophages, T cells, fibroblasts, and endothelial cells in response to infections, trauma, or tissue damage IL6 activates downstream signaling through its receptor, IL-6R, and the JAK/STAT3 pathway, driving acute-phase protein synthesis, such as CRP and fibrinogen, and promoting B cell differentiation into plasma cells Dysregulated IL6 expression is associated with chronic inflammation, autoimmune diseases like rheumatoid arthritis, and cancer progression, where it promotes tumor growth, survival, and angiogenesis IL6 also contributes to cytokine storm syndrome in conditions like COVID-19, where excessive IL6 leads to hyperinflammation and organ damage Targeting IL6 signaling with anti-IL6 therapies, such as tocilizumab, has shown efficacy in treating autoimmune diseases and cytokine-driven conditions

Características del producto

category

ELISA Kits


immunogen target

Interleukin 6 (IL6)


reactivity

Mouse


test range

7.8 pg/ml - 500 pg/ml


sensitivity

< 3.0 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

IL-6,BSF,HGF,HSF,IFNB2,CDF,B-cell stimulatory factor 2


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

IL6


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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