Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A/II-A (FCGR3A/FCGR2A) Antibody (PE)
273€ (0.1 mg)
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935106861
info@markelab.com
name
Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A/II-A (FCGR3A/FCGR2A) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx140569
tested applications
FCM
Description
Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A/II-A (FCGR3A/FCGR2A) Antibody (PE) is a Rat Monoclonal against Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A/II-A (FCGR3A/FCGR2A).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A/II-A (FCGR3A/FCGR2A) |
| Host | Rat |
| Reactivity | Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG2a Lambda |
| Clone ID | K571 |
| Purification | Purified by size-exclusion chromatography. |
| Size 1 | 0.1 mg |
| Tested Applications | FCM |
| Buffer | PBS solution with 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| Alias | CD16,FCG3,CD16A,FCGR3,IGFR3,IMD20,FCR-10,FCRIII,CD16-II,FCGRIII,FCRIIIA,FcGRIIIA,Low affinity immunoglobulin gamma Fc region receptor III-A,IgG Fc receptor III-A,IgG Fc receptor III-2 |
| Background | Antibody anti-FCGR3A |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
FCGR3A, or Fc gamma receptor IIIa, is a membrane-bound protein that plays a crucial role in the immune system, specifically in mediating immune responses through the recognition of the Fc region of IgG antibodies. This receptor is primarily expressed on the surface of natural killer (NK) cells, macrophages, monocytes, and dendritic cells, where it facilitates antibody-dependent cellular cytotoxicity (ADCC) and other immune responses. It is part of the broader family of Fc gamma receptors (FcγRs), which are responsible for binding to the Fc region of IgG antibodies, thereby linking humoral and cellular immunity. FCGR3A has garnered considerable attention in immunology due to its role in recognizing and responding to immune complexes, infected cells, and tumor cells coated with IgG antibodies. Variations in the gene encoding FCGR3A have been implicated in differential responses to infections, autoimmune diseases, and cancer therapies
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