Leukocyte Immunoglobulin Like Receptor Subfamily B Member 2 (LILRB2) Antibody

Este producto es parte de LILRB2 - leukocyte immunoglobulin like receptor B2
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195€ (20 µl)

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935106861
info@markelab.com
name
Leukocyte Immunoglobulin Like Receptor Subfamily B Member 2 (LILRB2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx136045
tested applications
ELISA, WB

Description

LILRB2 Antibody is a Rabbit Polyclonal against LILRB2.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Leukocyte Immunoglobulin Like Receptor Subfamily B Member 2 (LILRB2)
Immunogen: Recombinant protein corresponding to LILRB2. The exact sequence is proprietary.
Host
Rabbit
Reactivity
Mouse, Rat
Assay Type
Concentration: > 0.2 mg/ml
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/1000 - 1/4000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 65 kDa  Observed MW: 65 kDa
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q8N423
Gene ID
10288
NCBI Accession
NP_005865.3
Alias
Leukocyte immunoglobulin-like receptor subfamily B member 2,Leukocyte immunoglobulin-like receptor 2,ILT4,LIR2,CD85D,ILT-4,LIR-2,MIR10,MIR-10,CD85 antigen-like family member D,Immunoglobulin-like transcript 4,Monocyte/macrophage immunoglobulin-like receptor 10
Background
Antibody anti-LILRB2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

LILRB2, also known as Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2, ILT4 (Immunoglobulin-Like Transcript 4), or CD85d, is an inhibitory receptor expressed on immune cells, especially on myeloid cells, such as monocytes, macrophages, dendritic cells, and some granulocytes. It is part of the LILR family (leukocyte immunoglobulin-like receptors), which is encoded within the LRC (Leukocyte Receptor Complex) on chromosome 19q13.4. LILRB2 plays a major role in immune homeostasis by binding to MHC class I molecules and other ligands, leading to suppression of immune responses. This makes it a central player in controlling inflammation, self-tolerance, and response to chronic infections and tumors.

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