Leukocyte Immunoglobulin Like Receptor Subfamily B Member 2 (LILRB2) Antibody
195€ (20 µl)
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935106861
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name
Leukocyte Immunoglobulin Like Receptor Subfamily B Member 2 (LILRB2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx136045
tested applications
ELISA, WB
Description
LILRB2 Antibody is a Rabbit Polyclonal against LILRB2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Leukocyte Immunoglobulin Like Receptor Subfamily B Member 2 (LILRB2) |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/1000 - 1/4000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N423 |
| Gene ID | 10288 |
| NCBI Accession | NP_005865.3 |
| Alias | Leukocyte immunoglobulin-like receptor subfamily B member 2,Leukocyte immunoglobulin-like receptor 2,ILT4,LIR2,CD85D,ILT-4,LIR-2,MIR10,MIR-10,CD85 antigen-like family member D,Immunoglobulin-like transcript 4,Monocyte/macrophage immunoglobulin-like receptor 10 |
| Background | Antibody anti-LILRB2 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
LILRB2, also known as Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2, ILT4 (Immunoglobulin-Like Transcript 4), or CD85d, is an inhibitory receptor expressed on immune cells, especially on myeloid cells, such as monocytes, macrophages, dendritic cells, and some granulocytes. It is part of the LILR family (leukocyte immunoglobulin-like receptors), which is encoded within the LRC (Leukocyte Receptor Complex) on chromosome 19q13.4. LILRB2 plays a major role in immune homeostasis by binding to MHC class I molecules and other ligands, leading to suppression of immune responses. This makes it a central player in controlling inflammation, self-tolerance, and response to chronic infections and tumors.
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