Leukocyte Immunoglobulin Like Receptor Subfamily B Member 2 (LILRB2) Antibody

Este producto es parte de LILRB2 - leukocyte immunoglobulin like receptor B2
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312€ (60 µl)

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935106861
info@markelab.com
name
Leukocyte Immunoglobulin Like Receptor Subfamily B Member 2 (LILRB2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx126097
tested applications
WB

Description

LILRB2 Antibody is a Rabbit Polyclonal against LILRB2.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetLeukocyte Immunoglobulin Like Receptor Subfamily B Member 2 (LILRB2)
HostRabbit
ReactivityHuman
Recommended DilutionWB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified by affinity chromatography.
Size 160 µl
Size 2120 µl
Size 3200 µl
FormLiquid
Tested ApplicationsWB
BufferPBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ8N423
Gene ID10288
NCBI AccessionNP_005865.3
AliasLeukocyte immunoglobulin-like receptor subfamily B member 2,Leukocyte immunoglobulin-like receptor 2,ILT4,LIR2,CD85D,ILT-4,LIR-2,MIR10,MIR-10,CD85 antigen-like family member D,Immunoglobulin-like transcript 4,Monocyte/macrophage immunoglobulin-like receptor 10
BackgroundAntibody anti-LILRB2
StatusRUO
NoteConcentration: 1 mg/ml -

Descripción

LILRB2, also known as Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2, ILT4 (Immunoglobulin-Like Transcript 4), or CD85d, is an inhibitory receptor expressed on immune cells, especially on myeloid cells, such as monocytes, macrophages, dendritic cells, and some granulocytes. It is part of the LILR family (leukocyte immunoglobulin-like receptors), which is encoded within the LRC (Leukocyte Receptor Complex) on chromosome 19q13.4. LILRB2 plays a major role in immune homeostasis by binding to MHC class I molecules and other ligands, leading to suppression of immune responses. This makes it a central player in controlling inflammation, self-tolerance, and response to chronic infections and tumors.

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