Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) Antibody (PerCP / Cyanine 5.5)
598€ (100 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) Antibody (PerCP / Cyanine 5.5)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx347119
Tested Applications
FCM
Description
Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) Antibody (PerCP / Cyanine 5.5) is a Mouse Monoclonal against Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Conjugation | PerCP / Cyanine 5.5 |
| Isotype | IgG1 |
| Clone ID | B893 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | Q6GTX8 |
| Gene ID | 3903 |
| Alias | Leukocyte-associated immunoglobulin-like receptor 1,CD305,LAIR-1 |
| Background | Antibody anti-LAIR1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Leukocyte-associated immunoglobulin-like receptor 1 (LAIR1) is a critical immune regulatory receptor found primarily on leukocytes. It belongs to the immunoglobulin superfamily and functions predominantly as an inhibitory receptor that helps modulate immune responses to prevent overactivation and maintain immune homeostasis. LAIR1 is expressed on a wide array of immune cells, including T cells, B cells, NK cells, monocytes, and dendritic cells, where it plays a fundamental role in dampening immune cell activation to limit inflammation and protect against autoimmune reactions. The receptor primarily interacts with collagen and collagen-like ligands, commonly found in extracellular matrix proteins, which allows it to exert inhibitory signals in tissues rich in collagen. LAIR1’s role as an inhibitory receptor has garnered significant attention for its involvement in regulating immune cell activation, migration, and cytokine production. This regulatory function is crucial in autoimmune diseases, where loss of LAIR1 function can lead to unchecked immune responses. Additionally, its expression on a wide range of immune cells allows it to coordinate responses across both the innate and adaptive immune systems, and it has also been implicated in cancer immunology, particularly regarding how tumors may exploit LAIR1 signaling to evade immune detection.
Productos relacionados
Leukocyte Associated Immunoglobulin Like Receptor 1 (LAIR1) Antibody
The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T …
Ver producto
Human Leukocyte Associated Immunoglobulin Like Receptor 1 (LAIR1) Protein
Human Leukocyte Associated Immunoglobulin Like Receptor 1 (LAIR1) Protein is a recombinant Human protein expressed in E.…
Ver producto
Leukocyte Associated Immunoglobulin Like Receptor 1 (LAIR1) Antibody
Polyclonal Antibody to Leukocyte Associated Immunoglobulin Like Receptor 1 (LAIR1).…
Ver producto