Leukocyte Antigen CD37 / TSPAN26 (CD37) Antibody (FITC)
169€ (20 µg)
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Name
Leukocyte Antigen CD37 / TSPAN26 (CD37) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx314075
Description
CD37 Antibody (FITC) is a Rabbit Polyclonal against CD37 conjugated to FITC.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Leukocyte Antigen CD37 / TSPAN26 (CD37) Immunogen: Recombinant human Leukocyte antigen CD37 protein (109-237AA). |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P11049 |
| Gene ID | 951 |
| NCBI Accession | NP_001035120.1, NM_001040031.1, NP_001765.1, NM_001774.2 |
| OMIM | 151523 |
| Alias | GP52-40,TSPAN26,Leukocyte antigen CD37,Tetraspanin-26 |
| Background | Antibody anti-CD37 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD37 is a member of the tetraspanin family, a group of membrane proteins involved in cellular signaling, adhesion, migration, and immune responses. It is primarily expressed on leukocytes, especially on B cells, T cells, monocytes, and dendritic cells. CD37 plays a pivotal role in organizing membrane microdomains called tetraspanin-enriched microdomains (TEMs), which serve as platforms for cell signaling, facilitating the clustering of various membrane proteins, including integrins and other receptors involved in immune regulation. Unlike many other surface molecules, tetraspanins such as CD37 do not have a direct catalytic function but modulate the function of other molecules by influencing their spatial distribution and assembly in the membrane. This modulation affects immune cell functions, such as antigen presentation, cell adhesion, and migration, as well as B cell maturation and antibody production.
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