CD37 Antibody (FITC)
117€ (20 tests)
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Name
CD37 Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx228600
Tested Applications
FCM
Description
CD37 Antibody (FITC) is a Human Monoclonal Antibody against CD37.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: CD37 |
| Host | Mouse |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Isotype | IgG2b |
| Size 1 | 20 tests |
| Size 2 | 100 tests |
| Size 3 | 200 tests |
| Tested Applications | FCM |
| Buffer | PBS with 0.05% Proclin300, 1% BSA. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P11049 |
| Gene ID | 951 |
| Alias | GP52-40,TSPAN26,Leukocyte antigen CD37,Tetraspanin-26 |
| Background | Antibody anti-CD37 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD37 is a member of the tetraspanin family, a group of membrane proteins involved in cellular signaling, adhesion, migration, and immune responses. It is primarily expressed on leukocytes, especially on B cells, T cells, monocytes, and dendritic cells. CD37 plays a pivotal role in organizing membrane microdomains called tetraspanin-enriched microdomains (TEMs), which serve as platforms for cell signaling, facilitating the clustering of various membrane proteins, including integrins and other receptors involved in immune regulation. Unlike many other surface molecules, tetraspanins such as CD37 do not have a direct catalytic function but modulate the function of other molecules by influencing their spatial distribution and assembly in the membrane. This modulation affects immune cell functions, such as antigen presentation, cell adhesion, and migration, as well as B cell maturation and antibody production.
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