Leucine-Rich Repeat Neuronal Protein 4 (LRRN4) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Leucine-Rich Repeat Neuronal Protein 4 (LRRN4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx027525
tested applications
ELISA, WB, IHC
Description
Leucine-Rich Repeat Neuronal Protein 4 (LRRN4) Antibody is a Rabbit Polyclonal antibody for the detection of LRRN4. LRRN4 may play an important role in hippocampus-dependent long-lasting memory.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Leucine-Rich Repeat Neuronal Protein 4 (LRRN4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8WUT4 |
| Alias | NLRR4,NLRR-4,C20orf75,dJ1056H1.1, Neuronal leucine-rich repeat protein 4 |
| Background | Antibody anti-LRRN4 |
| Status | RUO |
Descripción
Leucine-Rich Repeat Neuronal 4 (LRRN4) is a member of the leucine-rich repeat (LRR) family of proteins, which are characterized by repetitive LRR motifs involved in protein-protein interactions. LRRN4 is primarily expressed in the nervous system, where it plays a role in neuronal development, synaptic plasticity, and axon guidance. Its expression pattern suggests involvement in the formation and maintenance of neuronal circuits. LRRN4 contains an extracellular domain rich in LRR motifs that mediate interaction with other proteins, a single transmembrane domain, and a short cytoplasmic tail. These features allow LRRN4 to function as a cell-surface receptor or adhesion molecule, facilitating communication between neurons and their environment. Functionally, LRRN4 is believed to participate in neuronal differentiation, axon pathfinding, and synapse formation. It may also play a role in maintaining the structural integrity of neural networks during development and adulthood. Emerging studies suggest that LRRN4 could be involved in neuronal repair processes following injury.
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