Leucine-Rich Repeat Neuronal Protein 3 (LRRN3) Antibody
169€ (20 µg)
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935106861
info@markelab.com
name
Leucine-Rich Repeat Neuronal Protein 3 (LRRN3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx318671
tested applications
ELISA, WB, IHC, IF/ICC
Description
LRRN3 Antibody is a Rabbit Polyclonal against LRRN3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Leucine-Rich Repeat Neuronal Protein 3 (LRRN3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H3W5 |
| Gene ID | 54674 |
| Alias | NLRR3,NLRR-3,FIGLER5, Neuronal leucine-rich repeat protein 3 |
| Background | Antibody anti-LRRN3 |
| Status | RUO |
| Note | Concentration: 0.196 mg/ml - |
Descripción
LRRN3 is another member of the LRR neuronal protein family and is predominantly expressed in the central nervous system. It plays a significant role in neural connectivity and synaptic modulation, contributing to the development of functional neural networks. LRRN3’s expression is tightly regulated during embryonic brain development, particularly in areas associated with sensory processing and motor control. This protein facilitates cell signaling and neural migration through its leucine-rich repeat domains, which promote specific interactions with other synaptic and extracellular proteins. LRRN3 is being studied for its potential involvement in neuropsychiatric conditions such as autism spectrum disorders (ASD) and schizophrenia, where synaptic and connectivity abnormalities are prevalent. Understanding LRRN3’s function could provide insights into therapeutic targets for these conditions.
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