Leucine-Rich Repeat Neuronal Protein 3 (LRRN3) Antibody
357.5€ (100 µg)
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935106861
info@markelab.com
name
Leucine-Rich Repeat Neuronal Protein 3 (LRRN3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx146210
tested applications
ELISA, WB, IHC
Description
LRRN3 Antibody is a Rabbit Polyclonal against LRRN3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Leucine-Rich Repeat Neuronal Protein 3 (LRRN3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC035133 |
| Alias | NLRR3,NLRR-3,FIGLER5, Neuronal leucine-rich repeat protein 3 |
| Background | Antibody anti-LRRN3 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
LRRN3 is another member of the LRR neuronal protein family and is predominantly expressed in the central nervous system. It plays a significant role in neural connectivity and synaptic modulation, contributing to the development of functional neural networks. LRRN3’s expression is tightly regulated during embryonic brain development, particularly in areas associated with sensory processing and motor control. This protein facilitates cell signaling and neural migration through its leucine-rich repeat domains, which promote specific interactions with other synaptic and extracellular proteins. LRRN3 is being studied for its potential involvement in neuropsychiatric conditions such as autism spectrum disorders (ASD) and schizophrenia, where synaptic and connectivity abnormalities are prevalent. Understanding LRRN3’s function could provide insights into therapeutic targets for these conditions.
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