Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 (LRIT1) Antibody (HRP)

Este producto es parte de LRIT - leucine rich repeat, Ig-like and transmembrane domains
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260€ (50 µl)

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935106861
info@markelab.com
name
Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 (LRIT1) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx349178
tested applications
ELISA

Description

Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 (LRIT1) Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP for the detection of Human LRIT1.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 (LRIT1)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
HRP
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G chromatography.
Size 1
50 µl
Size 2
100 µl
Size 3
200 µl
Size 4
1 ml
Form
Liquid
Tested Applications
ELISA
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9P2V4
Alias
PAL,LRRC21,FIGLER9,Retina-specific protein,Leucine-rich repeat-containing protein 21,Photoreceptor-associated LRR superfamily protein,Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1
Background
Antibody anti-LRIT1
Status
RUO

Descripción

LRIT1 is a transmembrane protein that is part of the leucine-rich repeat (LRR) superfamily, characterized by its involvement in protein-protein interactions, particularly within neuronal and sensory systems. The structure of LRIT1 includes leucine-rich repeat regions and immunoglobulin (Ig)-like domains, which contribute to its roles in signal transduction and cellular adhesion. It is predominantly expressed in retinal photoreceptor cells and is crucial for synaptic organization and retinal signal processing. LRIT1 mutations have been linked to congenital stationary night blindness (CSNB), highlighting its importance in visual neurotransmission and synaptic connectivity. Its localization and function suggest that LRIT1 is a key component of the ribbon synapses in the retina, mediating interactions between photoreceptors and bipolar cells.

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