Leucine-Rich Repeat, Immunoglobulin-Like Domain And Transmembrane Domain-Containing Protein 1 (LRIT1) Antibody

Name: Leucine-Rich Repeat, Immunoglobulin-Like Domain And Transmembrane Domain-Containing Protein 1 (LRIT1) Antibody
Brand: Abbexa
SKU: abx026248
Price: 292.5 EUR
Availability: OnlineOnly

Este producto es parte de LRIT - leucine rich repeat, Ig-like and transmembrane domains

Pida mas información

935106861

info@markelab.com

Precio

292.5€ (80 µl)

Antibody anti-LRIT1

proveedor

Abbexa

reference

abx026248

Tested Applications

ELISA, WB, FCM

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

Possible role in phototransduction.

Background

LRIT1 is a transmembrane protein that is part of the leucine-rich repeat (LRR) superfamily, characterized by its involvement in protein-protein interactions, particularly within neuronal and sensory systems. The structure of LRIT1 includes leucine-rich repeat regions and immunoglobulin (Ig)-like domains, which contribute to its roles in signal transduction and cellular adhesion. It is predominantly expressed in retinal photoreceptor cells and is crucial for synaptic organization and retinal signal processing. LRIT1 mutations have been linked to congenital stationary night blindness (CSNB), highlighting its importance in visual neurotransmission and synaptic connectivity. Its localization and function suggest that LRIT1 is a key component of the ribbon synapses in the retina, mediating interactions between photoreceptors and bipolar cells.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Leucine-Rich Repeat, Immunoglobulin-Like Domain And Transmembrane Domain-Containing Protein 1 (LRIT1)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, FCM

purification

Purified through a protein A column, followed by peptide affinity purification.

recommended dilution

WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS containing 0.09% sodium azide.

size 1

80 µl

size 2

400 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

LRIT1

dry ice

availability

Shipped within 5-10 working days.

alias

PAL,LRRC21,FIGLER9,Retina-specific protein,Leucine-rich repeat-containing protein 21,Photoreceptor-associated LRR superfamily protein,Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1

uniprot id

https://www.uniprot.org/uniprotkb/Q9P2V4

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