Leucine-Rich Repeat-Containing Protein 46 (LRRC46) Antibody

357.5€ (100 µg)
Este producto es parte de LRRC - Leucine-rich repeat-containing protein
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357.5€ (100 µg)

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935106861
info@markelab.com
name
Leucine-Rich Repeat-Containing Protein 46 (LRRC46) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx036346
tested applications
ELISA, WB, IHC

Descripción del producto

Rabbit Polyclonal against the LRRC46 protein.

Documents del producto

Instrucciones
Data sheet
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Especificaciones del producto

AliasLRRC46
AvailabilityShipped within 7-15 working days.
BackgroundAntibody anti-LRRC46
BufferPrior to lyophilization: 1% BSA and 0.02% NaN3.
CategoryPrimary Antibodies
ClonalityPolyclonal
ConjugationUnconjugated
Dry IceNo
FormLyophilized
HostRabbit
Immunogen TargetLeucine-Rich Repeat-Containing Protein 46 (LRRC46)
IsotypeIgG
NameLeucine-Rich Repeat-Containing Protein 46 (LRRC46) Antibody
NoteConcentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. -
Price357.5
ProviderAbbexa
PurificationPurified by antigen affinity column chromatography.
ReactivityHuman
Recommended DilutionELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Referenceabx036346
Size 1100 µg
Size 21 mg
StatusRUO
StorageStore at -20 °C. Avoid repeated freeze/thaw cycles.
Tested ApplicationsELISA, WB, IHC

Descripcion del producto en español

Background en español

LRRC46 is a protein associated with microtubule organization and ciliogenesis studies indicate it plays a critical role in the assembly and stability of motile cilia particularly in tissues such as the respiratory tract and reproductive system where ciliary function is essential for mucus clearance and gamete transport LRRC46 has been shown to interact with axonemal components of cilia contributing to the regulation of ciliary beat frequency and coordination mutations in LRRC46 have been associated with primary ciliary dyskinesia (PCD) a disorder characterized by impaired ciliary function and chronic respiratory infections its expression is also linked to processes involving cellular polarity and signaling through the ciliary apparatus further studies aim to elucidate its precise molecular functions and its potential as a therapeutic target in ciliopathies and other disorders related to defective cilia

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