Leucine-Rich Repeat-Containing Protein 46 (LRRC46) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Leucine-Rich Repeat-Containing Protein 46 (LRRC46) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx026225
tested applications
ELISA, WB, IHC
Description
Leucine-Rich Repeat-Containing Protein 46 (LRRC46) Antibody is a Rabbit Polyclonal antibody against LRRC46.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Leucine-Rich Repeat-Containing Protein 46 (LRRC46) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96FV0 |
| Alias | LRRC46 |
| Background | Antibody anti-LRRC46 |
| Status | RUO |
| Note | Concentration: 0.35 mg/ml - |
Descripción
LRRC46 is a protein associated with microtubule organization and ciliogenesis studies indicate it plays a critical role in the assembly and stability of motile cilia particularly in tissues such as the respiratory tract and reproductive system where ciliary function is essential for mucus clearance and gamete transport LRRC46 has been shown to interact with axonemal components of cilia contributing to the regulation of ciliary beat frequency and coordination mutations in LRRC46 have been associated with primary ciliary dyskinesia (PCD) a disorder characterized by impaired ciliary function and chronic respiratory infections its expression is also linked to processes involving cellular polarity and signaling through the ciliary apparatus further studies aim to elucidate its precise molecular functions and its potential as a therapeutic target in ciliopathies and other disorders related to defective cilia
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