Leucine-Rich Repeat-Containing Protein 2 (LRRC2) Antibody

169€ (20 µg)
Este producto es parte de LRRC - Leucine-rich repeat-containing protein
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169€ (20 µg)

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935106861
info@markelab.com
name
Leucine-Rich Repeat-Containing Protein 2 (LRRC2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx301665
tested applications
ELISA, IHC

Descripción del producto

LRRC2 Antibody is a Rabbit Polyclonal against LRRC2.

Documents del producto

Instrucciones
Data sheet
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Especificaciones del producto

OMIM607180
AliasLRRC2
AvailabilityShipped within 5-10 working days.
BackgroundAntibody anti-LRRC2
Buffer0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
CategoryPrimary Antibodies
ClonalityPolyclonal
ConjugationUnconjugated
Dry IceNo
FormLiquid
Gene ID79442
HostRabbit
Immunogen TargetLeucine-Rich Repeat-Containing Protein 2 (LRRC2)
IsotypeIgG
NameLeucine-Rich Repeat-Containing Protein 2 (LRRC2) Antibody
Price169
ProviderAbbexa
PurificationPurified by Protein G.
Purity> 95%
ReactivityHuman
Recommended DilutionIHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Referenceabx301665
Size 120 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 51 mg
StatusRUO
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Tested ApplicationsELISA, IHC
UniProt IDQ9BYS8

Descripcion del producto en español

Background en español
LRRC2 is a protein involved in the regulation of cell signaling and cytoskeletal organization primarily expressed in neural and endothelial cells it has been identified as a modulator of the Wnt/β-catenin signaling pathway which is essential for cellular proliferation differentiation and migration studies indicate LRRC2's involvement in blood-brain barrier integrity as it regulates interactions between endothelial cells and the extracellular matrix contributing to vascular stability and selective permeability LRRC2 has also been implicated in neural development where its role in maintaining axonal guidance and synaptic stability has been suggested through interactions with cytoskeletal proteins mutations in LRRC2 have been associated with neurodevelopmental disorders and conditions involving vascular dysfunction emerging research links LRRC2 to angiogenesis and vascular remodeling in pathological contexts such as cancer and stroke further exploration is needed to fully characterize its function and potential therapeutic applications in neurovascular and oncological conditions
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