Leucine Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) Antibody
52€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Leucine Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx015336
Tested Applications
ELISA, WB
Description
Rabbit polyclonal antibody against LGR4 protein. Immunogen region is Internal.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Leucine Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) Immunogen: The antiserum was produced against synthesized peptide derived from internal of human LGR4. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BXB1 |
| Alias | LGR4,GPR48,leucine-rich repeat-containing G protein-coupled receptor 4,leucine-rich repeat containing G protein-coupled receptor 4,DPSL,BNMD17 |
| Background | Antibody anti-LGR4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
LGR4 is a member of the leucine-rich repeat-containing G protein-coupled receptor (LGR) family, which is activated by R-spondins, a group of proteins that regulate Wnt signaling. LGR4 plays a significant role in tissue development, differentiation, and homeostasis, particularly in the epithelial cells of various organs, including the gastrointestinal tract, kidney, and skin. It is involved in modulating Wnt/β-catenin signaling pathways, which are crucial for cell proliferation, stem cell maintenance, and differentiation. LGR4 is implicated in regulating processes such as embryogenesis, organogenesis, and tissue repair. Dysregulation of LGR4 signaling has been associated with conditions like cancer, particularly colorectal cancer, and disorders of tissue regeneration. LGR4 also plays a role in controlling blood pressure and fluid balance, with potential therapeutic applications in hypertension and renal diseases.
Productos relacionados
Leucine Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) Antibody
Rabbit polyclonal antibody against LGR4 protein. Immunogen region is Internal.…
Ver producto
Leucine Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) Antibody
Rabbit Polyclonal against the LGR4 protein.…
Ver producto Leucine Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) Antibody
Leucine Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) Antibody is a Rabbit Polyclonal antibody for the dete…
Ver producto