Leucine Rich Repeat Containing 45 (LRRC45) Antibody (HRP)

Este producto es parte de LRRC - Leucine-rich repeat-containing protein
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169€ (20 µg)

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935106861
info@markelab.com
name
Leucine Rich Repeat Containing 45 (LRRC45) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx336348
tested applications
ELISA

Description

LRRC45 Antibody (HRP) is a Rabbit Polyclonal against LRRC45.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Leucine Rich Repeat Containing 45 (LRRC45)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
HRP
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q96CN5
Gene ID
201255
Alias
LRRC45
Background
Antibody anti-LRRC45
Status
RUO

Descripción

LRRC45 is a centrosomal protein implicated in microtubule organization and mitotic spindle formation during cell division its expression is highly enriched in proliferative tissues where it regulates centrosomal dynamics and ensures proper chromosome segregation studies suggest that LRRC45 interacts with key components of the centrosome and microtubule network to maintain cellular architecture and division fidelity dysregulation of LRRC45 has been associated with chromosomal instability and cancer progression particularly in aggressive tumors characterized by abnormal mitosis LRRC45 may also play a role in ciliogenesis by regulating microtubule anchoring and centrosome function ongoing research is focused on characterizing its interactions with centrosomal proteins and exploring its potential as a therapeutic target for cancers involving mitotic defects further understanding of its molecular function could provide insights into centrosome biology and its role in genomic stability

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