Leucine Rich Repeat Containing 45 (LRRC45) Antibody
169€ (20 µg)
169€ (20 µg)
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name
Leucine Rich Repeat Containing 45 (LRRC45) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx334192
tested applications
ELISA, IHC, IF/ICC
Descripción del producto
LRRC45 Antibody is a Rabbit Polyclonal against LRRC45.
Documents del producto
Instrucciones
Data sheet
Especificaciones del producto
| Alias | LRRC45 |
| Availability | Shipped within 5-10 working days. |
| Background | Antibody anti-LRRC45 |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Category | Primary Antibodies |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Dry Ice | No |
| Form | Liquid |
| Gene ID | 201255 |
| Host | Rabbit |
| Immunogen Target | Leucine Rich Repeat Containing 45 (LRRC45) |
| Isotype | IgG |
| Name | Leucine Rich Repeat Containing 45 (LRRC45) Antibody |
| Price | 169 |
| Provider | Abbexa |
| Purification | Purified by Protein G. |
| Purity | > 95% |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/200 - 1/500, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Reference | abx334192 |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Status | RUO |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Tested Applications | ELISA, IHC, IF/ICC |
| UniProt ID | Q96CN5 |
Descripcion del producto en español
Background en español
LRRC45 is a centrosomal protein implicated in microtubule organization and mitotic spindle formation during cell division its expression is highly enriched in proliferative tissues where it regulates centrosomal dynamics and ensures proper chromosome segregation studies suggest that LRRC45 interacts with key components of the centrosome and microtubule network to maintain cellular architecture and division fidelity dysregulation of LRRC45 has been associated with chromosomal instability and cancer progression particularly in aggressive tumors characterized by abnormal mitosis LRRC45 may also play a role in ciliogenesis by regulating microtubule anchoring and centrosome function ongoing research is focused on characterizing its interactions with centrosomal proteins and exploring its potential as a therapeutic target for cancers involving mitotic defects further understanding of its molecular function could provide insights into centrosome biology and its role in genomic stability
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