Leucine-Rich Repeat And Immunoglobulin-Like Domain-Containing Nogo Receptor-Interacting Protein 2 (LINGO2) Antibody
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Description
The function of this protein is unknown.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Leucine-Rich Repeat And Immunoglobulin-Like Domain-Containing Nogo Receptor-Interacting Protein 2 (LINGO2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q7L985 |
| Alias | LERN3,LRRN6CLeucine-rich repeat neuronal protein 6C,Leucine-rich repeat neuronal protein 3,Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 |
| Background | Antibody anti-LINGO2 |
| Status | RUO |
Descripción
LINGO2 shares structural similarities with LINGO1, containing leucine-rich repeats and Ig-like domains, and is primarily expressed in the CNS. While its exact physiological roles are less well-characterized than LINGO1, LINGO2 is thought to contribute to neuronal signaling and synaptic function. Studies suggest that LINGO2 may regulate neurodevelopmental processes and could play a role in synaptic plasticity and connectivity. Genetic variations in the LINGO2 gene have been linked to neurological and psychiatric conditions, including essential tremor and depression, although the underlying mechanisms remain under investigation. Its expression patterns and potential involvement in CNS homeostasis make it an emerging focus for understanding neural development and dysfunction.
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