Kin of IRRE-Like Protein 2 (KIRREL2) Antibody
169€ (20 µg)
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935106861
info@markelab.com
name
Kin of IRRE-Like Protein 2 (KIRREL2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx318590
tested applications
ELISA, WB
Description
KIRREL2 Antibody is a Rabbit Polyclonal against KIRREL2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Kin of IRRE-Like Protein 2 (KIRREL2) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/1000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6UWL6 |
| Gene ID | 84063 |
| NCBI Accession | NP_001316459.1 |
| OMIM | 607762 |
| Alias | NLG1,NEPH3,FILTRIN,Nephrin-like protein 3,Kin of irregular chiasm-like protein 2, Kin of IRRE-like protein 2 |
| Background | Antibody anti-KIRREL2 |
| Status | RUO |
Descripción
KIRREL2, also called nephrin-like protein 2, is primarily expressed in the nervous system and endocrine tissues. It functions in synaptic organization, contributing to neuronal connectivity and cell signaling. KIRREL2 features extracellular Ig-like domains that mediate interactions with other adhesion molecules, facilitating synaptic development and plasticity. In the endocrine system, it may regulate hormone-secreting cells, although its specific roles remain under investigation. Dysregulation of KIRREL2 has been implicated in neurological disorders and synaptic defects, highlighting its importance in brain health and neurodevelopment.
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