Kirre Like Nephrin Family Adhesion Molecule 2 (KIRREL2) Antibody

Background

KIRREL2, also called nephrin-like protein 2, is primarily expressed in the nervous system and endocrine tissues. It functions in synaptic organization, contributing to neuronal connectivity and cell signaling. KIRREL2 features extracellular Ig-like domains that mediate interactions with other adhesion molecules, facilitating synaptic development and plasticity. In the endocrine system, it may regulate hormone-secreting cells, although its specific roles remain under investigation. Dysregulation of KIRREL2 has been implicated in neurological disorders and synaptic defects, highlighting its importance in brain health and neurodevelopment.