Interleukin 31 (IL31) Antibody
221€ (50 µg)
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935106861
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name
Interleukin 31 (IL31) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx325004
tested applications
ELISA, WB
Description
IL31 Antibody is a Rabbit Polyclonal against IL31.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interleukin 31 (IL31) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000 - 1/20000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6EBC2 |
| Gene ID | 386653 |
| Alias | IL-31 |
| Background | Antibody anti-IL31 |
| Status | RUO |
Descripción
Interleukin 31 (IL31) is a cytokine belonging to the IL-6 cytokine family that plays a central role in the regulation of immune responses and is heavily implicated in inflammatory processes, particularly in chronic pruritic (itching) skin disorders. IL-31 is primarily produced by activated T helper 2 (Th2) cells, a subset of T cells involved in allergic responses and the regulation of immune responses to extracellular pathogens. IL-31 was discovered as a cytokine that can link the immune system with the nervous system, particularly in the skin, where it triggers pruritus and inflammatory responses. The IL-31 receptor is widely expressed, being found on keratinocytes, fibroblasts, epithelial cells, and immune cells, which suggests its involvement in skin and tissue homeostasis
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