interleukin-31 (IL31) Antibody

Product specifications

Primary Antibodies

interleukin-31 (IL31)

Rabbit

Human

Optimal dilutions/concentrations should be determined by the end user.

Polyclonal

Unconjugated

IgG

Purified

100 µg

Lyophilized

ELISA, WB

Prior to lyophilization: PBS.

Shipped within 3-7 working days.

Store lyophilized at 2°C to 8°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

No

Q6EBC2

IL-31

Antibody anti-IL31

RUO

Concentration: Prior to lyophilization: 1.0 mg/ml - 

Descripción

Interleukin 31 (IL31) is a cytokine belonging to the IL-6 cytokine family that plays a central role in the regulation of immune responses and is heavily implicated in inflammatory processes, particularly in chronic pruritic (itching) skin disorders. IL-31 is primarily produced by activated T helper 2 (Th2) cells, a subset of T cells involved in allergic responses and the regulation of immune responses to extracellular pathogens. IL-31 was discovered as a cytokine that can link the immune system with the nervous system, particularly in the skin, where it triggers pruritus and inflammatory responses. The IL-31 receptor is widely expressed, being found on keratinocytes, fibroblasts, epithelial cells, and immune cells, which suggests its involvement in skin and tissue homeostasis

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