Interleukin 24 (IL24) Antibody
169€ (20 µg)
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935106861
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name
Interleukin 24 (IL24) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx306736
tested applications
ELISA, IHC
Description
IL24 Antibody is a Rabbit Polyclonal against IL24.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interleukin 24 (IL24) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13007 |
| Gene ID | 11009 |
| NCBI Accession | NP_001172085.1, NM_001185156.1, NP_001172086.1, NM_001185157.1, NP_001172087.1, NM_001185158.1, NP_006841.1, NM_006850.3 |
| OMIM | 604136 |
| Alias | C49A,FISP,MDA7,MOB5,ST16,IL10B,Melanoma differentiation-associated gene 7 protein,Suppression of tumorigenicity 16 protein |
| Background | Antibody anti-IL24 |
| Status | RUO |
Descripción
Interleukin 24 (IL24) is a cytokine belonging to the IL-10 family, which includes other related cytokines such as IL-10, IL-19, IL-20, IL-22, and IL-26. IL-24 was first identified as melanoma differentiation-associated gene-7 (mda-7), due to its expression being upregulated during the process of melanoma cell differentiation. It plays a key role in immune regulation, cell survival, apoptosis, and the modulation of inflammatory responses. IL-24 is unique in its ability to induce apoptosis selectively in cancer cells without affecting normal cells, making it a promising therapeutic target for cancer treatment. IL-24 is produced by a variety of immune cells, including macrophages, monocytes, and T-cells, and is involved in both immune modulation and inflammation. Its expression can be triggered by pro-inflammatory signals, such as TNF-α and IFN-γ
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