Interleukin 24 (IL24) Antibody

Este producto es parte de IL24 - interleukin 24
Interleukin 24 (IL24) Antibody
169€ (20 µg)

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Name
Interleukin 24 (IL24) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx306736
Tested Applications
ELISA, IHC

Description

IL24 Antibody is a Rabbit Polyclonal against IL24.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Interleukin 24 (IL24)
Immunogen: Recombinant human Interleukin-24 protein (52-207AA).
Host
Rabbit
Reactivity
Human
Recommended Dilution
IHC: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, IHC
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q13007
Gene ID
11009
NCBI Accession
NP_001172085.1, NM_001185156.1, NP_001172086.1, NM_001185157.1, NP_001172087.1, NM_001185158.1, NP_006841.1, NM_006850.3
OMIM
604136
Alias
C49A,FISP,MDA7,MOB5,ST16,IL10B,Melanoma differentiation-associated gene 7 protein,Suppression of tumorigenicity 16 protein
Background
Antibody anti-IL24
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

Interleukin 24 (IL24) is a cytokine belonging to the IL-10 family, which includes other related cytokines such as IL-10, IL-19, IL-20, IL-22, and IL-26. IL-24 was first identified as melanoma differentiation-associated gene-7 (mda-7), due to its expression being upregulated during the process of melanoma cell differentiation. It plays a key role in immune regulation, cell survival, apoptosis, and the modulation of inflammatory responses. IL-24 is unique in its ability to induce apoptosis selectively in cancer cells without affecting normal cells, making it a promising therapeutic target for cancer treatment. IL-24 is produced by a variety of immune cells, including macrophages, monocytes, and T-cells, and is involved in both immune modulation and inflammation. Its expression can be triggered by pro-inflammatory signals, such as TNF-α and IFN-γ

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