Interleukin 24 (IL24) Antibody
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935106861
info@markelab.com
Precio
169€ (20 µg)
Antibody anti-IL24
proveedor
Abbexareference
abx306736Tested Applications
ELISA, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
IL24 Antibody is a Rabbit Polyclonal against IL24.
Background
Interleukin 24 (IL24) is a cytokine belonging to the IL-10 family, which includes other related cytokines such as IL-10, IL-19, IL-20, IL-22, and IL-26. IL-24 was first identified as melanoma differentiation-associated gene-7 (mda-7), due to its expression being upregulated during the process of melanoma cell differentiation. It plays a key role in immune regulation, cell survival, apoptosis, and the modulation of inflammatory responses. IL-24 is unique in its ability to induce apoptosis selectively in cancer cells without affecting normal cells, making it a promising therapeutic target for cancer treatment. IL-24 is produced by a variety of immune cells, including macrophages, monocytes, and T-cells, and is involved in both immune modulation and inflammation. Its expression can be triggered by pro-inflammatory signals, such as TNF-α and IFN-γ
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Interleukin 24 (IL24)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, IHC
purity
> 95%
purification
Purified by Protein G.
recommended dilution
IHC: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
IL24
dry ice
No
availability
Shipped within 5-10 working days.
alias
C49A,FISP,MDA7,MOB5,ST16,IL10B,Melanoma differentiation-associated gene 7 protein,Suppression of tumorigenicity 16 protein
uniprot id
NCBI accession
NP_001172085.1, NM_001185156.1, NP_001172086.1, NM_001185157.1, NP_001172087.1, NM_001185158.1, NP_006841.1, NM_006850.3
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